Announcement PDF ASX ANNOUNCEMENT 12 May 2026 Probiotical SpA exclusive supply agreement extended to 2028 Highlights ● Biome has executed a two-year extension to its existing exclusive supply agreement with Probiotical SpA, one of Biome’s key supply chain partners since incorporation in 2018 ● Extension replaces the previous agreement, which was due to expire in June 2026, and now runs through 2028 on existing terms ● Extension provides Biome and Probiotical with the platform to continue their long-standing relationship as Biome scales its international footprint ● Biome’s Australian manufacturing onshoring program, a Biome-led initiative, continues to progress and is well underway Biome Australia Limited (ASX: BIO) (Biome or the Company) is pleased to announce that it has executed a two-year extension to its existing exclusive supply agreement with Probiotical SpA. Probiotical has been a strain partner of Biome since the Company was incorporated in 2018. Two-year extension on existing terms The previous exclusive supply agreement was due to expire in June 2026. The executed extension takes the agreement through 2028 on the existing commercial terms. The extension provides Biome and Probiotical with the runway to continue executing on existing arrangements as Biome scales its international footprint across Australia, Canada, the United Kingdom, Ireland and New Zealand. Long-standing partnership in Biome’s broader supply chain strategy Probiotical has been one of Biome’s most important strategic partners since the Company was founded, and the two businesses share a long-standing working relationship. Biome and Probiotical intend to continue developing the partnership in step with Biome’s growth profile. In parallel, Biome’s Australian manufacturing onshoring program, a Biome-led initiative, continues to progress and is well underway. The Company will provide a further update on Australian manufacturing within calendar 2026. Commentary Blair Vega Norfolk, Founder and Managing Director of Biome Australia, said: "Probiotical has been one of our most important strategic partners since the Company was founded. This two-year extension on existing terms gives both businesses the certainty to continue executing as Biome scales internationally, and we look forward to continuing to develop the partnership alongside the ongoing investment we are making in Australian manufacturing capability." –ENDS– Approved for release by the Biome Australia board of directors. Investor Hub Biome has launched a new interactive investor hub. To view a video presentation of this announcement, ask questions or sign up for future company updates, please visit the investor hub at https://investorhub.biomeaustralia.com/. About Biome Australia Limited Biome Australia develops, licences, commercialises and markets innovative, evidence-based live biotherapeutics (probiotics) and complementary medicines, many of which are supported by clinical research. Biome aims to improve health outcomes and quality of life, and make its products accessible to all. Incorporated in Australia in 2018, Biome distributes locally and abroad. In partnership with some of the world's leading organisations in microbiome research and development, Biome produced several unique live biotherapeutic (probiotic) products with innovative delivery technologies that improve their stability and efficacy to create its flagship range of complementary medicines: Activated Probiotics®. Supported by clinical research, including randomised double-blind placebo- controlled trials, Activated Probiotics and Activated Therapeutics help prevent and support the management of various health concerns, including low mood and sleep, bone health, iron malabsorption, mild eczema and IBS. Through practitioner-only distribution, Biome is committed to educating health professionals on the newfound systemic health effects of the gut microbiota, helping them to provide innovative, evidence-based natural medicines for the management of some of humanity's most prevalent and chronic health concerns. For more information visit: www.biomeaustralia.com Investor Relations Lauren Dwyer corporate@biomeaustralia.com (03) 9017 5800 Forward Looking Statements This release may contain forward looking statements, including but not limited to projections, guidance on future revenues, earnings, other potential synergies and estimates and the future performance of Biome (Forward Looking Statements). 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