Announcement PDF Jan 2024 Strategy Meeting February 2026 H1 FY26 Results & Company Presentation Blair Vega Norfolk Founder & Managing Director Biome Australia #1 fastest growing probiotic brand, ACTIVATED PROBIOTICS, in Australian pharmacy 100% of product range in growth. Full-margin growth without promotional discounting. Proprietary IP pipeline with first human clinical trial underway BMB18TM strain, 240-participant RCT with La Trobe University Record revenue, record profit, 40% growth $12.40m H1 revenue | $6.45m Q2 revenue | $1.18m net profit | 8 consecutive EBITDA quarters H1 FY26 Financial Scorecard Record results across all key metrics Revenue $12.40m +40% vs PCP Adj. EBITDA $1.47m 8th consecutive quarter Net Profit $1.18m +172% vs PCP Gross Margin 61.1% Achieved (1H25: 61.0%) Op. Cash Flow $2.09m $3.21m turnaround EPS 0.53c +165% vs PCP Operating Leverage Now Visible Earnings growth significantly outpacing revenue growth Revenue & Cash Receipts ($m) EBITDA* (Adj) & Net Profit ($m) Revenue +40% +100% Net Profit +172% Cash Receipts +62% EBITDA Market Opportunity Large, growing global market with significant runway in Australia and internationally Global Probiotics Market ~US$75B+ estimated 2025, growing 7-8% CAGR Dietary supplements the fastest growing segment at ~12% CAGR Australian Probiotics Market ~A$600M estimated domestic market Biome is #1 growth brand with significant headroom to scale How Biome Has De-Risked the Opportunity #1 growth brand Category leadership established across community pharmacy, TWC, Priceline, and wholesale Revenue at scale Annualised run rate of ~$25.8m with 40% growth, proving product-market fit and repeat demand 5 markets live Practitioner-only model validated in Australia and now replicating in Canada, Ireland, UK, and New Zealand Distribution built 7,000+ points from 100 in FY19. TAM ~12,000. Current penetration ~58% with significant upside About Biome Australia Biome Australia (ASX: BIO) is focused on becoming a global leader in the complementary medicine industry, offering clinically-proven, condition-specific probiotic products fueled by novel clinical research programs to cement and extend the evidence base of its probiotic products. Activated Probiotics, Biome’s flagship range of novel live-biotherapeutics (probiotics), was created in partnership with world leading organisations in microbiome research and utilises innovative delivery technologies that improves their stability and efficacy. Biome has a B Corporation certification, a designation that a business is meeting high standards of verified performance, accountability and transparency. A range of condition specific probiotics Activated Probiotics has selected specific strains for various health conditions and aspects of health to create a range of precision probiotics 7 Selective formulations with clinically validated applications 8 Clinically Proven Product Range The majority of products are supported by published clinical trials on the finished product Mood, Sleep & Depression Biome Lift™ 3 RCTs on finished product Clinically proven for mood, sleep quality, and subthreshold depression Bone Health Biome Osteo™ Published in The Lancet 78% reduction in bone loss vs placebo in landmark clinical trial Immune & Respiratory Biome Breathe™ RCT on finished product 64% reduction in asthma events vs placebo Cholesterol Biome Cholesterol™ 5 RCTs on finished product Significant LDL reduction. Proven safe alongside statins Skin: Eczema Biome Eczema™ RCT on finished product 52% reduction in eczema SCORAD score vs placebo Skin: Acne Biome Acne™ RCT on finished product 39% reduction in acne lesions vs placebo Iron Absorption Biome Iron+™ Clinical trial published More than 50% increase in iron absorption with a fruit juice Children's Health Biome Daily Kids™ Federation Uni clinical trial Paediatric-specific formulation with clinically documented strains This depth of clinical evidence across a full product range is unique in the global probiotics market and underpins the practitioner recommendation model Clinical Evidence as Competitive Moat The evidence base is what makes the practitioner model work. Without it, there is no recommendation. Clinically Documented Strains Every product formulated with strains supported by published clinical evidence. Not marketing claims. Practitioners require this standard before recommending. Condition-Specific Formulations 18 products across two brands, each targeting a defined health condition. Enables practitioners to prescribe by indication, exactly as they would a pharmaceutical product. Complementary to Medical Treatment Positioned alongside, not instead of, medical interventions. Practitioners recommend with confidence because the products complement existing care plans and are free from any known drug interactions. Why This Is Difficult to Replicate Clinical evidence requires years of investment Practitioner trust built through education Recommendation drives pharmacy ranging Scan data proves performance, deepens ranging New entrants cannot shortcut this process Adjunct Medication Opportunities ATC medication category Medication volume July 2020–June 2021 Activated Probiotics product with adjunct opportunities General Anti-infectives 10M Prescriptions per year Biome Advanced™ Probiotic To help restore the balance of beneficial gut bacteria after antibiotic use Nervous System 48M Prescriptions per year Biome Lift™ Probiotic To support healthy mood balance and enhance sleep quality Respiratory System 12M Prescriptions per year Biome Breathe™ Probiotic To help stimulate a healthy immune system response in children Dermatological 3M Prescriptions per year Biome Eczema™ Probiotic To help reduce the symptoms of mild eczema Musculo-skeletal System 7M Prescriptions per year Biome Osteo™ Probiotic To help promote bone healthy in adults Cardiovascular System 29M Prescriptions per year Biome Cholesterol™ Probiotic To help support healthy cholesterol levels in healthy adults Source: http://medicarestatistics.humanservices.gov.au/statistics/pbs_group.jsp Condition-specific range enables multiple products per patient, positioned alongside medical treatment Activated Probiotics are recommended by practitioners as complementary to existing medical treatment, not as alternatives. This positions Biome alongside pharmaceutical and medical interventions rather than competing with mass-market supplements. The clinical evidence base gives practitioners the confidence to actively recommend, creating a fundamentally different demand model to traditional VMS brands. Market Position The fastest growing brand in the biggest category in pharmacy #1 Community Pharmacy (ex CW) Probiotic brand by revenue Fastest growing in category #2 Terry White Chemmart Total vitamins Fastest growing in category 48%+ Priceline Pharmacy MAT scan sales growth Significant headroom for further growth #1 Wholesale (Symbion/API) Growth brand VMS category 100% of range in growth The Pull Model Full-margin growth without promotional discounting Traditional VMS Model Push Growth driven by promotional cycles and discounting Margin erosion as brands scale Price-sensitive, substitutable demand Retailer controls the relationship High cost of customer acquisition Biome Model Pull Growth driven by practitioner recommendation 61% gross margin achieved and maintained at scale Evidence-based demand, high brand loyalty ~2.5 units per transaction, 6 visits per year (TWCM data) Consumer seeks the product by name The Practitioner Flywheel Our competitive moat: practitioner endorsement drives category leadership 1 Practitioner Education Health-qualified consultants deliver clinical training 2 Practitioner Recommendation Trusted endorsement drives patient purchase 3 Pharmacy Purchase ~2.5 units per transaction, 6 visits/year (TWCM data) 4 Scan Data Validates Category growth drives deeper ranging 5 Category Leadership #1 growth brand reinforces practitioner confidence Repeat purchase behaviour compounds growth across all channels Training and Education Driven Sales Model — Practitioner Only Unique Education and Service Model Drives Sales in Australia, UK and NZ Education and Service Support The Biome sales team is a mix of health qualified practitioner education consultants and territory managers Practitioner education consultants undertake high level product detailing and training in community pharmacy and with independent health practitioners High quality training and education develops stronger trust and relationships with health practitioners Biomes support leads to active recommendations of Biome Australia products Digital educational content and assets effectively support the national sales team in servicing practitioner markets Health Clinics are provided to key accounts to gain trust and develop existing accounts Rolling 12 Months and Quarterly Sales Revenue ● Biome has grown its Australian distribution from 100 distribution points in 2019 to 7000+ in FY26 — the total addressable distribution market for Biome in our local market is ~12,000. ● Existing distribution (7000+) is expected to be ~58% developed at the close of H1 FY26. This leaves significant potential for scale in both number of accounts and average account revenue through Vision 27 and beyond. ● FY26 estimated 7500 by end of FY26. Distribution growth and business development Clinical & IP Pipeline Proprietary IP strategy building long-term competitive advantage Discovery Preclinical Ethics Approval Human Trial Results & Product Dev BMB18TM Lactobacillus plantarum BMB18TM Human Clinical Trial Trial Design: Randomised, double-blind, placebo-controlled | Participants: 240 | Partner: La Trobe University Commenced: February 2026 | Strain Bank: Registered with DSMZ (Germany) | IP Status: Proprietary to Biome Australia Existing Clinical Evidence Base (30+ RCT studies on Biome’s finished products) Including: Biome Lift (mood & sleep) Biome Osteo (bone health) Biome Daily Kids (paediatric) BMB18™ : Proprietary Strain Development Lactobacillus plantarum BMB18 | 100% owned by Biome Australia | DSMZ registered In Vitro Study Results Completed by European research partner Immune Modulation Strong ability to modulate immune responses and inflammation Oxidative Stress Reduction Demonstrated capacity to reduce oxidative stress markers Gut Barrier Integrity Maintained intestinal barrier integrity, reducing leaky gut Human Clinical Trial Commenced February 2026 Design: Randomised, double-blind, placebo-controlled Participants: 240 across two active dosage levels Partner: La Trobe University Duration: 12 months Cost: ~$140,000 (within existing R&D budget) Registry: ANZCTR (Australia New Zealand Clinical Trials) Target Conditions Digestive symptoms (bloating, discomfort) Sleep disturbances Mood disturbances Quality of life outcomes Development Pipeline Strain Identification Commercial Validation DSMZ Deposit In Vitro Characterisation Human Clinical Trial Product Development 100% Biome-owned IP Reduces COGS via proprietary strain Future licensing opportunity Long-term balance sheet asset International Expansion Four markets now contributing to revenue Established Australia 7000+ distribution points TWC, Priceline, Symbion, API Mecca, Go Vita Growing Canada Fullscript (practitioner platform) Ecotrend (national wholesale) Territory managers in ON, BC & Q Launched Ireland & UK Uniphar (wholesale distribution) Pharmacy access established Launched July 2025 Launched New Zealand Propharma (EBOS Group) Green Cross Health Dual-channel model H2 Outlook & Growth Catalysts Winter Immunity Campaign First major above-the-line national advertising campaign. Outdoor, digital, and co-branded activity with key retail partners. Timed to coincide with peak demand period. International Momentum Canada accelerating with Fullscript now live alongside Ecotrend. Ireland and New Zealand partnerships continuing to build. UK market under development. BMB18TM Clinical Trial 240-participant randomised controlled trial underway with La Trobe University. Results will support proprietary product development and strengthen IP portfolio. Category Expansion Active product pipeline under evaluation to extend the Activated Probiotics and Activated Therapeutics ranges into new therapeutic categories. Investment Case Category Leader #1 fastest growing probiotic brand in Australia's biggest pharmacy category. 100% of range in growth. Premium Margin Model 61% gross margin achieved at scale without promotional discounting. Pull-based demand driven by practitioner endorsement sustains full-margin growth with long product lifecycles. Operating Leverage Proven Net profit up 172%. Operating cash flow turnaround of $3.28m. Eighth consecutive EBITDA positive quarter. Proprietary IP Pipeline BMB18TM strain in human clinical trial. DSMZ registered. Long-term balance sheet asset under development. International Optionality Four markets live. Practitioner-only model replicating across Canada, Ireland, and New Zealand. Fully Funded Growth No capital required. Borrowings halved. Cash generative. Annualised run rate of ~$25.8m ($6.45m Q2 exit run rate). Shaping the Industry Biome plays an active role in advancing standards, regulation, and education across the complementary medicine industry Complementary Medicines Australia (CMA) Board Director CMA is the peak industry body representing the complementary medicines sector in Australia, advocating for regulatory frameworks, market access, and evidence-based standards across the industry. International Probiotics Association (IPA) Board Director The IPA is the global voice of the probiotics industry, representing companies across research, manufacturing, and distribution. Membership includes leading probiotic producers worldwide. What This Reflects Direct input into regulatory and policy decisions that shape the Australian and global probiotics landscape Industry recognition of Biome's scientific credibility and evidence-based approach to product development Relationships with the world's leading probiotic researchers, manufacturers, and distribution partners Visibility and influence that support commercial partnerships and international market access Contact details Blair Norfolk, CEO Lauren Dwyer, CFO Email corporate@biomeaustralia.com Websites biomeaustralia.com activatedprobiotics.com.au Disclaimer This presentation and the information contained within it (the “information”) has been prepared solely for the use and benefit of the person to whom it is provided (the “recipient”). 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